"It will be a repetition of the barbarism and savagery which we saw in Nimrud, Hatra and Mosul," he added.
Last month a seven-minute video emerged, showing IS militants destroying the historic Assyrian city of Nimrud, which dates back to the 13th century B. The ancient site is near the Islamic State-controlled city of Mosul in northern Iraq.
* The image of the creature with four legs and a human head is a nephilm, an offspring of a fallen angel and human woman in which earth people mistook them for gods, star people.
In February, the jihadists obliterated ancient artifacts in the Mosul Museum and blew up the Mosul Public Library using homemade bombs.
The remains of the ancient caravan city of Palmyra stand in the middle of the desolate Tadmorean Desert in Syria.
UNESCO describes Palmyra as a landmark of "outstanding universal value," an "oasis in the Syrian desert" northeast of Damascus.
"If IS enters Palmyra, it will spell its destruction," Abdulkarim told AFP.
"If the ancient city falls, it will be an international catastrophe.